Alan Gutierrez

Alan Gutierrez is a research assistant with the Sabeti Lab working as a part of the ENCODE Consortium Functional Characterization Center’s efforts to develop and apply next-generation non-coding CRISPR screens. Under the mentorship of Dr. Steven Reilly, he has helped to develop HCR-FlowFISH—a novel technology to identify cis-regulatory elements in the genome.

Alan graduated from Vassar College in 2018 with a B.A. in Biochemistry and a minor in Russian Studies. There, he conducted research on Wingless signaling regulation in Drosophila melanogaster. In addition, he was a part of the First Generation 9, a sociological research team that investigated the experiences of first generation college students at a liberals arts institution.

Alan is also a proud alumnus of Harvard Medical School’s Summer Honors Undergraduate Research Program (SHURP), where he studied the possible contribution of mitochondrial architecture to Diffuse Large B-Cell Lymphoma metabolic subtypes at the Dana-Farber Cancer Institute under the mentorship of Dr. Nika Danial.

Alan plans to attend medical school in the near future and mold his unique research experiences into an exceptional career in medicine.

Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone

Cell. 2015.
Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC

Discovery Of Novel Rhabdoviruses In The Blood Of Healthy Individuals From West Africa

PLoS Negl Trop Dis 17;9(3):e0003631
Stremlau MH, Andersen KG, Folarin OA, Grove JN, Odia I, Ehiane PE, Omoniwa O, Omoregie O, Jiang PP, Yozwiak NL, Matranga CB, Yang X, Gire SK, Winnicki SM, Tariyal R, Schaffner SF, Okokhere PO, Okogbenin S, Akpede GO, Asogun DA, Agbonlahor DE, Walker PJ, Tesh RB, Levin JZ, Garry RF, Sabeti PC, Happi CT

Enhanced Methods For Unbiased Deep Sequencing Of Lassa And Ebola RNA Viruses In Clinical And Biological Samples.

Genome Biol 15(11):519
Matranga CB, Andersen KG, Winnicki SM, Busby M, Gladden AD, Tewhey R, Stremlau M, Berlin A, Gire SK, England E, Moses LM, Mikkelsen TS, Odia I, Ehiane PE, Folarin O, Goba A, Kahn SH, Grant DS, Honko A, Hensley L, Happi C, Garry RF, Malboeuf CM, Birren BW, Gnirke A, Levin JZ, Sabeti PC

Clinical Illness And Outcomes In Patients With Ebola In Sierra Leone

N Engl J Med 371(22):2092-100
Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RSG, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, Andersen KG, Winnicki SM, Schaffner SF, Park DJ, Yozwiak NL, Jiang PP, Kargbo D, Jalloh S, Fonnie M, Sinnah V, French I, Kovoma A, Kamara FK, Tucker V, Konuwa E, Sellu J, Mustapha I, Foday M, Yillah M, Kanneh F, Saffa S, Massally JL, Boisen ML, Branco LM, Vandi MA, Grant DS, Happi C, Gevao SM, Fletcher TE, Fowler RA, Bausch DG, Sabeti PC, Khan SH, Garry RF for the KGH Lassa Fever Program, the Viral Hemorrhagic Fever Consortium and the WHO Clinical Response Team

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Science 345(6202):1369-72
Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki SM, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang PP, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JL, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH, Sabeti PC.

Research capacity. Enabling the genomic revolution in Africa.

Science 344(6190):1346-8
H3Africa Consortium

Identifying Recent Adaptations In Large-Scale Genomic Data

Cell 152(4):703-713
Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki SM, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RNK, Hill AVS, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC

Early host-pathogen interactions in a marine bivalve: Crassostrea virginica pallial mucus modulates Perkinsus marinus growth and virulence.

Dis Aquat Organ. 104(3):237-47
Pales Espinosa E, Winnicki SM, Allam B.

Early host-pathogen interactions in marine bivalves: evidence that the alveolate parasite Perkinsus marinus infects through the oyster mantle during rejection of pseudofeces.

ALAN GUTIERREZ

SELECTED PUBLICATIONS

Science 344(6190):1346-8
H3Africa Consortium

Cell 152(4):703-713
Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki SM, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RNK, Hill AVS, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC

Dis Aquat Organ. 104(3):237-47
Pales Espinosa E, Winnicki SM, Allam B.

J Invertebr Pathol. 113(1):26-34
Allam B, Carden WE, Ward JE, Ralph G, Winnicki SM, Pales Espinosa E.

ALAN GUTIERREZ

SELECTED PUBLICATIONS

Science 344(6190):1346-8 H3Africa Consortium

Cell 152(4):703-713 Grossman SR*, Andersen KG*, Shlyakhter I*, Tabrizi S*, Winnicki SM, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RNK, Hill AVS, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC

Dis Aquat Organ. 104(3):237-47 Pales Espinosa E, Winnicki SM, Allam B.

J Invertebr Pathol. 113(1):26-34 Allam B, Carden WE, Ward JE, Ralph G, Winnicki SM, Pales Espinosa E.

Science 344(6190):1346-8
H3Africa Consortium

Cell 152(4):703-713
Grossman SR, Andersen KG, Shlyakhter I, Tabrizi S, Winnicki SM, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RNK, Hill AVS, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC

Dis Aquat Organ. 104(3):237-47
Pales Espinosa E, Winnicki SM, Allam B.

J Invertebr Pathol. 113(1):26-34
Allam B, Carden WE, Ward JE, Ralph G, Winnicki SM, Pales Espinosa E.