Al Ozonoff PhD CPPS is Associate Professor of Pediatrics at Harvard Medical School, Director of Pandemic Preparedness at the Broad Institute, and Managing Director of Sentinel, a program focused on genomic and data-driven infectious disease surveillance in West Africa. He serves as Senior Advisor to Dr. Sabeti and Chief of Staff of the Sabeti Lab. In these roles, he leads the design and implementation of Sentinel’s surveillance systems and partnerships while contributing to the scientific programs and collaborations of the Sabeti Lab.

Trained in mathematics, statistics, epidemiology, and data science, Al develops systems for population-based surveillance and the improvement of health in children and adults. His work centers on methods for detecting and monitoring health and disease across clinical and public health settings. As a surveillance methodologist, he works across infectious disease surveillance, patient safety, and healthcare quality, with a focus on data systems that inform decision-making. He is a faculty scientist within the Precision Vaccines Program at Boston Children’s Hospital and contributes to international efforts in vaccine science and pediatric health, including through leadership roles with international networks focused on pediatric health such as the Penta Foundation, and as a founding member of the vaccine safety network INSIS.

Al’s graduate and post-doctoral training was in mathematics (University of California, Santa Barbara, under D. Darren Long) and biostatistics (Harvard School of Public Health, under Marcello Pagano). Over more than 20 years, he has co-authored over 225 peer-reviewed publications. He was Principal Investigator of two R01 grant awards: a 3-year project funded by the Centers for Disease Control and Prevention (CDC) BioSense Program, “Improving syndromic surveillance by data integration” (R01 PH000021-02), and a 5-year project funded by the Agency for Healthcare Research and Quality (AHRQ), “Patient safety surveillance using machine learning and free text clinical” (R01 HS026246-01A1).

During the early phases of the COVID-19 pandemic, he led the Clinical and Data Coordinating Center for IMPACC, a national immunophenotyping study funded by the National Institute for Allergy and Infectious Diseases (NIH/NIAID), coordinating data integration and analysis across a multi-institutional clinical network. His work has also contributed to the development of surveillance methods and data infrastructure for patient safety and healthcare quality in hospital settings. In 2016–17, he was one of 12 Harvard Medical School Fellows in Bioethics.

Outside of work, Al enjoys spending time with his family and learning from teachers in contemplative traditions. He has played semi-professional football for over 25 years, most recently with the Massachusetts Warriors of the New England Football League.