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ANTONIO SOLANO

antonio

Antonio Solano was a User Experience and Data Visualization researcher in the lab from 2017 to 2018. He primarily worked on data visualization and design of genomic data for epidemiological surveillance.

He is currently a senior data visualization and user experience designer for a private company called TriNetX, based in Cambridge, MA. He is currently designing a platform for clinical trial feasibility analysis, clinical trial recruitment, and real-world, retrospective analyses, which include clinical outcomes, comparative effectiveness studies, and patient journeys, among others.

He is currently working on designing one of the most advanced visual query builders for clinical cohort definitions available to researchers around the globe. The ability to define “virtual” cohorts of patients with great details allows researchers to target specific populations, including those with rare diseases. These interfaces allow users to modify treatments in near-real time, such as in the case of UTMB Health’s Blocker Burn Center in Galveston, TX. These same interfaces and visualizations are currently helping the FDA’s epidemiologists monitor the use of critical drugs and vaccines for COVID-19 patients. Antonio’s work also supports the FDA’s Sentinel Initiative, particularly during the COVID-19 pandemic. Additionally, he occasionally engages in consulting projects, particularly in the area of data visualization for genomics. Two recent projects include the Jackson Laboratory and the NextStrain initiative at the Fred Hutch Cancer Center, both of which are NCI-designated Cancer Research Centers.

Additionally, thanks to his work and experiences in the Sabeti Lab, he is now able to mentor graduate and undergraduate students in Costa Rica (where he is originally from) and is actively participating as an external advisor on thesis evaluation committees.

Antonio sees his key accomplishments during his time in the lab as conducting user research with Harvard University students and HUHS clinicians to propose a project for infectious disease surveillance, monitoring and prediction. This work supported a $400K grant from the Bill and Melinda Gates Foundation that the lab obtained shortly after. While he was focusing on Mumps as a primary pathogen, the work he developed at the time, such as mobile symptom trackers, has now been replicated in many countries due to the COVID-19 pandemic. He also co-authored a novel visualization platform for the analysis of viral MSAs called NX4 that drastically reduces the cognitive load for the users, completely runs in the browser, and offers a visual alternative to the typical colored matrices used for MSAs.

“The lab is forward-thinking, open to unconventional ideas, and draws value from diversity in all of its forms.”

Personal Website | LinkedIn | Twitter

SELECTED PUBLICATIONS

Ebola Virus Epidemiology, Transmission, and Evolution during Seven Months in Sierra Leone

Cell. 2015.
Park DJ, Dudas G, Wohl S, Goba A, Whitmer SL, Andersen KG, Sealfon RS, Ladner JT, Kugelman JR, Matranga CB, Winnicki SM, Qu J, Gire SK, Gladden-Young A, Jalloh S, Nosamiefan D, Yozwiak NL, Moses LM, Jiang PP, Lin AE, Schaffner SF, Bird B, Towner J, Mamoh M, Gbakie M, Kanneh L, Kargbo D, Massally JL, Kamara FK, Konuwa E, Sellu J, Jalloh AA, Mustapha I, Foday M, Yillah M, Erickson BR, Sealy T, Blau D, Paddock C, Brault A, Amman B, Basile J, Bearden S, Belser J, Bergeron E, Campbell S, Chakrabarti A, Dodd K, Flint M, Gibbons A, Goodman C, Klena J, McMullan L, Morgan L, Russell B, Salzer J, Sanchez A, Wang D, Jungreis I, Tomkins-Tinch C, Kislyuk A, Lin MF, Chapman S, MacInnis B, Matthews A, Bochicchio J, Hensley LE, Kuhn JH, Nusbaum C, Schieffelin JS, Birren BW, Forget M, Nichol ST, Palacios GF, Ndiaye D, Happi C, Gevao SM, Vandi MA, Kargbo B, Holmes EC, Bedford T, Gnirke A, Ströher U, Rambaut A, Garry RF, Sabeti PC

Discovery Of Novel Rhabdoviruses In The Blood Of Healthy Individuals From West Africa

PLoS Negl Trop Dis 17;9(3):e0003631
Stremlau MH, Andersen KG, Folarin OA, Grove JN, Odia I, Ehiane PE, Omoniwa O, Omoregie O, Jiang PP, Yozwiak NL, Matranga CB, Yang X, Gire SK, Winnicki SM, Tariyal R, Schaffner SF, Okokhere PO, Okogbenin S, Akpede GO, Asogun DA, Agbonlahor DE, Walker PJ, Tesh RB, Levin JZ, Garry RF, Sabeti PC, Happi CT

Enhanced Methods For Unbiased Deep Sequencing Of Lassa And Ebola RNA Viruses In Clinical And Biological Samples.

Genome Biol 15(11):519
Matranga CB, Andersen KG, Winnicki SM, Busby M, Gladden AD, Tewhey R, Stremlau M, Berlin A, Gire SK, England E, Moses LM, Mikkelsen TS, Odia I, Ehiane PE, Folarin O, Goba A, Kahn SH, Grant DS, Honko A, Hensley L, Happi C, Garry RF, Malboeuf CM, Birren BW, Gnirke A, Levin JZ, Sabeti PC

Clinical Illness And Outcomes In Patients With Ebola In Sierra Leone

N Engl J Med 371(22):2092-100
Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RSG, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, Andersen KG, Winnicki SM, Schaffner SF, Park DJ, Yozwiak NL, Jiang PP, Kargbo D, Jalloh S, Fonnie M, Sinnah V, French I, Kovoma A, Kamara FK, Tucker V, Konuwa E, Sellu J, Mustapha I, Foday M, Yillah M, Kanneh F, Saffa S, Massally JL, Boisen ML, Branco LM, Vandi MA, Grant DS, Happi C, Gevao SM, Fletcher TE, Fowler RA, Bausch DG, Sabeti PC, Khan SH, Garry RF for the KGH Lassa Fever Program, the Viral Hemorrhagic Fever Consortium and the WHO Clinical Response Team

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

Science 345(6202):1369-72
Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, Winnicki SM, Matranga CB, Malboeuf CM, Qu J, Gladden AD, Schaffner SF, Yang X, Jiang PP, Nekoui M, Colubri A, Coomber MR, Fonnie M, Moigboi A, Gbakie M, Kamara FK, Tucker V, Konuwa E, Saffa S, Sellu J, Jalloh AA, Kovoma A, Koninga J, Mustapha I, Kargbo K, Foday M, Yillah M, Kanneh F, Robert W, Massally JL, Chapman SB, Bochicchio J, Murphy C, Nusbaum C, Young S, Birren BW, Grant DS, Scheiffelin JS, Lander ES, Happi C, Gevao SM, Gnirke A, Rambaut A, Garry RF, Khan SH, Sabeti PC.

Research capacity. Enabling the genomic revolution in Africa.

Science 344(6190):1346-8
H3Africa Consortium

Identifying Recent Adaptations In Large-Scale Genomic Data

Cell 152(4):703-713
Grossman SR*, Andersen KG*, Shlyakhter I*, Tabrizi S*, Winnicki SM, Yen A, Park DJ, Griesemer D, Karlsson EK, Wong SH, Cabili M, Adegbola RA, Bamezai RNK, Hill AVS, Vannberg FO, Rinn JL, 1000 Genomes Project, Lander ES, Schaffner SF, Sabeti PC

Early host-pathogen interactions in a marine bivalve: Crassostrea virginica pallial mucus modulates Perkinsus marinus growth and virulence.

Dis Aquat Organ. 104(3):237-47
Pales Espinosa E, Winnicki SM, Allam B.

Early host-pathogen interactions in marine bivalves: evidence that the alveolate parasite Perkinsus marinus infects through the oyster mantle during rejection of pseudofeces.

J Invertebr Pathol. 113(1):26-34
Allam B, Carden WE, Ward JE, Ralph G, Winnicki SM, Pales Espinosa E.

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