Katherine Siddle – Sabeti Lab

KATHERINE SIDDLE, Ph.D.

Katie has been a postdoctoral fellow in the Sabeti Lab since May 2015, where she is developing genomic approaches to improve the characterization of viral diversity in acute febrile infections.

Katie completed her BA and MPhil in Biological Anthropology at the University of Cambridge, UK. She obtained her Ph.D. in 2014 from the Institut Pasteur and the Université Pierre et Marie Curie, in Paris, France, where she studied microRNA regulation in the human innate immune response to infection.

Katie is currently supported by a long-term postdoctoral fellowship from the Human Frontiers in Science Program.

SELECTED PUBLICATIONS

Bacterial Infection Drives the Expression Dynamics of microRNAs and Their isomiRs.

PLoS Genetics. 2015.
Siddle KJ , Tailleux L, Deschamps M, Loh YHE, Deluen C, Gicquel B, Antoniewski C, Barreiro LB, Farinelli L, Quintana-Murci L.

The Red Queen's long race: human adaptation to pathogen pressure.

Current Opinion in Genetics and Development. 2014.
Siddle KJ & Quintana-Murci L

A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection.

Genome Research. 2014.
Siddle KJ , Deschamps M, Tailleux L, Nédélec Y, Pothlichet J, Lugo-Villarino G, Libri V, Gicquel B, Neyrolles O, Laval G, Patin E, Barreiro LB, Quintana-Murci L.

The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists.

Nature Communications. 2014.
Patin E, Siddle KJ , Laval G, Quach H, Harmant C, Becker N, Froment A, Régnault B, Lemée L, Gravel S, Hombert JM, Van der Veen L, Dominy NJ, Perry GH, Barreiro LB, Verdu P, Heyer E, Quintana-Murci L.

Bases Adjacent to Mononucleotide Repeats Show an Increased Single Nucleotide Polymorphism Frequency in the Human Genome.

Bioinformatics. 2011.
Siddle KJ , Goodship JA, Keavney BD, Santibanez-Koref MF

Genetic diversity and evidence for population admixture in Batak Negritos from Palawan.

American Journal of Physical Anthropology. 2011.
Scholes C, Siddle KJ, Ducourneau A, Crivellaro F, Jarve M, Rootsi S, Bellatti M, Tabbada K, Mormina M, Reidla M, Villems R, Kivisild T, Lahr MM, Migliano AB
(* equal contributors)

KATHERINE SIDDLE, Ph.D.

SELECTED PUBLICATIONS

PLoS Genetics. 2015. Siddle KJ , Tailleux L, Deschamps M, Loh YHE, Deluen C, Gicquel B, Antoniewski C, Barreiro LB, Farinelli L, Quintana-Murci L.

Current Opinion in Genetics and Development. 2014. Siddle KJ & Quintana-Murci L

Genome Research. 2014. Siddle KJ , Deschamps M, Tailleux L, Nédélec Y, Pothlichet J, Lugo-Villarino G, Libri V, Gicquel B, Neyrolles O, Laval G, Patin E, Barreiro LB, Quintana-Murci L.

Nature Communications. 2014. Patin E, Siddle KJ , Laval G, Quach H, Harmant C, Becker N, Froment A, Régnault B, Lemée L, Gravel S, Hombert JM, Van der Veen L, Dominy NJ, Perry GH, Barreiro LB, Verdu P, Heyer E, Quintana-Murci L.

Bioinformatics. 2011. Siddle KJ , Goodship JA, Keavney BD, Santibanez-Koref MF